Medrio vs OpenClinica
On the evidence we track, OpenClinica leads this comparison with a composite score of 59/100. Scores are only directly comparable because these tools share a category; the full breakdown and every source is below.
Capabilities
Feature-by-feature on the axes that matter for clinical trial management. “-” means undocumented, not absent.
What each one is
The product in its own terms, so the numbers below have context.
Medrio
A validated electronic data capture system for clinical trials offering enterprise-grade functionality with a user-friendly interface, supported by experienced project managers and data analysts.
OpenClinica
LeaderOpenClinica provides electronic data capture, reporting, and operational modules for clinical research teams. It combines study data collection with tools for patient recruitment, informed consent, randomization, and analytics, supporting researchers from small academic teams to large-scale pharmaceutical organizations.
Pricing
List pricing as published by each vendor, with the date we read it. Always verify at the source before you buy.
Medrio
Pricing not documented yet.
OpenClinica
LeaderFrom $750/month for Launch (30-day free trial). Core $3,000/month per study. Advanced $3,750/month. Enterprise custom annual pricing.
- Launch$750/month, no annual contract
- EDC only
- Shared EDC with standard data limits
- Standard templates
- Study-level config and user controls
- 24/7 self-service compliance and docs
- +3 more
- CoreContact sales
- EDC + Reporting & Analytics
- Run multiple studies with volume discounts
- Free expert-managed study build
- Dedicated, fully isolated EDC
- Fully customizable form library
- +5 more
- AdvancedContact sales
- Core Bundle + Choice of Add-on Module
- Built for 3+ concurrent studies
- Free expert-managed study build
- Advanced analytics included, no data limits
- Complete admin with MFA and SSO
- +4 more
- Enterprise & AcademicContact sales
- Every module unlocked program-wide
- Supports 20+ studies, no data limits, multi-year flexibility
- Free expert-managed study build
- Enterprise analytics across program
- Program-level customizable templates
- +4 more
Platform & deployment
Where each product runs and how it can be hosted. A dash means undocumented, not unsupported.
Integrations
What each product connects to. Counts come from the vendor's own integration directory where one exists.
Medrio
Not documented yet.
OpenClinica
Leader- CDISC ODM
- S-cubed Biometrics
- RESTful APIs
Medrio or OpenClinica: which one depends on you
A composite score cannot know your constraints. Describe them and both get re-weighted against what you actually need, with the evidence behind every position.
Free to run, no account needed to start. How the evaluation works
Comparison generated from independently-sourced facts. Every value links to its source and retrieval date. See the method.