Comparison

Florence eBinders vs OpenClinica

On the evidence we track, OpenClinica leads this comparison with a composite score of 59/100. Scores are only directly comparable because these tools share a category; the full breakdown and every source is below.

Machine formatsMarkdownJSONGraphQLAll open, no key required.
Florence eBinders47
★OpenClinica59
Score
vioscaleAI score
Florence eBinders47 / 100low · 14%
OpenClinica59 / 100medium · 59%
Pricing
Free tier
Florence eBinders–
OpenClinica✓
Model
Florence eBinderscommercial
OpenClinicafreemium
Price level
Florence eBinders–
OpenClinicahigh
Starting price
Florence eBinders–
OpenClinica$750
Transparent
Florence eBinders–
OpenClinica✓
Integrations
Count
Florence eBinders5
OpenClinica3
Security
Certifications
Gdpr
Florence eBinders–
OpenClinica✓
Hipaa
Florence eBinders–
OpenClinica✓
Iso27001
Florence eBinders–
OpenClinica✓
Soc2
Florence eBinders✓
OpenClinica✓
Market
Availability

Capabilities

Feature-by-feature on the axes that matter for clinical trial management. “-” means undocumented, not absent.

Capabilities
Fda 21 cfr part 11 electronic signatures
Florence eBinders✓
OpenClinica✓
Edc electronic data capture forms
Florence eBinders-
OpenClinica✓
Etmf electronic trial master file storage
Florence eBinders✓
OpenClinica-
Patient recruitment CRM and screening
Florence eBinders-
OpenClinica✓
Randomization and trial supply management irts
Florence eBinders-
OpenClinica✓
Clinical investigator payment and stipend tracking
Florence eBinders-
OpenClinica-
Decentralized clinical trial dct remote monitoring
Florence eBinders✓
OpenClinica✓
Adverse event and safety reporting
Florence eBinders-
OpenClinica-
HIPAA baas business associate agreement
Florence eBinders-
OpenClinica✓
SOC2 type ii
Florence eBinders✓
OpenClinica✓
ISO 27001
Florence eBinders-
OpenClinica✓
Pricing model
Florence eBinders-
OpenClinicaPer study tier

What each one is

The product in its own terms, so the numbers below have context.

Florence eBinders

A cloud-based system for clinical trial operations that centralizes regulatory file management, enables remote monitoring of study sites, and automates communication between sponsors, CROs, and research facilities. It provides document tracking, electronic signatures, and integration with existing trial systems.

Independently observed

OpenClinica

Leader

OpenClinica provides electronic data capture, reporting, and operational modules for clinical research teams. It combines study data collection with tools for patient recruitment, informed consent, randomization, and analytics, supporting researchers from small academic teams to large-scale pharmaceutical organizations.

Independently observed

Pricing

List pricing as published by each vendor, with the date we read it. Always verify at the source before you buy.

Florence eBinders

Pricing not documented yet.

OpenClinica

Leader
from $750/moSubscriptionFree tier30-day trial

From $750/month for Launch (30-day free trial). Core $3,000/month per study. Advanced $3,750/month. Enterprise custom annual pricing.

  • Launch$750/month, no annual contract
    • EDC only
    • Shared EDC with standard data limits
    • Standard templates
    • Study-level config and user controls
    • 24/7 self-service compliance and docs
    • +3 more
  • CoreContact sales
    • EDC + Reporting & Analytics
    • Run multiple studies with volume discounts
    • Free expert-managed study build
    • Dedicated, fully isolated EDC
    • Fully customizable form library
    • +5 more
  • AdvancedContact sales
    • Core Bundle + Choice of Add-on Module
    • Built for 3+ concurrent studies
    • Free expert-managed study build
    • Advanced analytics included, no data limits
    • Complete admin with MFA and SSO
    • +4 more
  • Enterprise & AcademicContact sales
    • Every module unlocked program-wide
    • Supports 20+ studies, no data limits, multi-year flexibility
    • Free expert-managed study build
    • Enterprise analytics across program
    • Program-level customizable templates
    • +4 more
as of verify ↗

Platform & deployment

Where each product runs and how it can be hosted. A dash means undocumented, not unsupported.

Platforms
Web
Florence eBinders✓
OpenClinica✓
Deployment
Cloud / SaaS
Florence eBinders✓
OpenClinica✓

Integrations

What each product connects to. Counts come from the vendor's own integration directory where one exists.

Florence eBinders

5 total
  • Clinical Trial Management System (CTMS)
  • Electronic Health Records (EHR)
  • Electronic Data Capture (EDC)
  • Email
  • Single Sign-On (SAML)
Independently observed

OpenClinica

Leader
3 total
  • CDISC ODM
  • S-cubed Biometrics
  • RESTful APIs
Independently observed
Still deciding?

Florence eBinders or OpenClinica: which one depends on you

A composite score cannot know your constraints. Describe them and both get re-weighted against what you actually need, with the evidence behind every position.

Free to run, no account needed to start. How the evaluation works

Comparison generated from independently-sourced facts. Every value links to its source and retrieval date. See the method.